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2017 Jul 25
Solubility: DMSO : ≥ 50 mg/mL (159
33)26-8-3-2-4-9-26/h2-13
CAS Number: 1229002-07-6
and cholesterol homoeostasis
Eltanexor (KPT-8602) Size:Contact [email protected] for quotation 2017 Jul 25Eltanexor, also known as KPT 8602, is a second generation exportin 1 inhibitor. KPT 8602 demonstrates potent activity against acute lymphoblastic leukemia. KPT 8602 is well tolerated and highly active against AML blasts and leukemia initiating cells. Eltanexor shows improved efficacy and in vivo tolerability in hematological malignancies. KPT 8602 is a potent inhibitor of AML cells in cell based viability assays. KPT 8602 inhibits XPO1 cargo